Evommune Sets Sights on $160M IPO Amid Federal Shutdown

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Evommune Sets Sights on $160M IPO Amid Federal Shutdown

Evommune, a California-based biotech company, has announced its intention to raise up to $160 million through an initial public offering (IPO) on the New York Stock Exchange. The company plans to offer nearly 9.4 million shares of common stock priced between $15 and $17 per share, with an additional 30-day option for underwriters to purchase 1.4 million more shares.

Navigating the Federal Shutdown

Despite the ongoing federal shutdown, Evommune aims to complete its IPO by November 5th using Section 8(a) of the Securities Act. This provision allows registrations to take effect 20 days after filing, bypassing potential delays caused by the shutdown. The company has stated that it will reevaluate this strategy if the shutdown ends before the planned IPO date.

Pipeline Focus and Funding Allocation

Evommune's IPO proceeds are earmarked for advancing its clinical-stage pipeline, which focuses on inflammatory conditions. The company's lead asset, EVO756, is an orally available small-molecule inhibitor of the MRGPRX2 receptor. This drug candidate has recently completed a Phase II study in chronic inducible urticaria and is currently in mid-stage testing for chronic spontaneous urticaria.

Additionally, Evommune is developing EVO301, a fusion protein targeting the inflammatory cytokine IL-18. The company initiated a program for EVO301 in moderate-to-severe atopic dermatitis in March, with plans to expand studies to ulcerative colitis and Crohn's disease.

Industry Context and Market Trends

Evommune's IPO announcement follows a trend of recent public offerings in the biotech sector. Notable examples include MapLight Therapeutics, which aims to raise $227.3 million for Alzheimer's disease and schizophrenia drug development, and LB Pharma, which closed a $285 million IPO to fund its neuroscience pipeline. Other recent IPOs in the industry include Metsera, Maze Therapeutics, and Aardvark, indicating a robust market for biotech public offerings despite broader economic challenges.

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